Our story begins in Sicily where we found Jane and Ajira recovering from their last mission and taking on some dicey high-paying freelance work that brings them to the heart of VENICE, Italy where they meet up with their contact and take on a group of gangs terrorizing the city. While this is all underway, they themselves soon become hunted by the famous MK KILLER after he finds out they were behind his last unsuccessful gig. With Jane's world being turned upside down, they are soon joined by the rest of her regular cast Detective Maureen Fernandez, her best friend, and Doctor Seth as they all try to help Jane stay alive while being hunted down for a big payout.